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Towards Clinically Relevant Explanations for Type-2 Diabetes Risk Prediction

Shruthi Chari [email protected] 1234-5678-9012 Rensselaer Polytechnic Institute (RPI)110 8th StTroyNYUSA Prithwish Chakraborty Center for Computational Health, IBM ResearchYorktown HeightsNYUSA [email protected] Mohamed Ghalwash Center for Computational Health, IBM ResearchYorktown HeightsNYUSA [email protected] Oshani Seneviratne Rensselaer Polytechnic InstituteTroyNYUSA [email protected] Daniel Gruen Rensselaer Polytechnic InstituteTroyNYUSA [email protected] Pablo Meyer Rojas Center for Computational Health, IBM ResearchYorktown HeightsNYUSA [email protected]  and  Deborah L. McGuinness Rensselaer Polytechnic InstituteTroyNYUSA [email protected]
(2018)
Abstract.

With the increased need for AI models to be more explainable, there have been efforts to apply these techniques in high-precision domains like healthcare. From our past user studies and interaction with medical experts, we find that they appreciate explanations to help them understand model predictions better. To this end, we have begun to explore techniques to generate user-centered explanations that are contextualized by authoritative literature from clinical practice guidelines and backed by AI model predictions and post-hoc explanations. We present and discuss our methodology and initial results for this approach for a type-2 diabetes risk prediction use case.

user-centered explainability, contextualized explanations, clinical use case
copyright: acmcopyrightjournalyear: 2018doi: 10.1145/1122445.1122456conference: Woodstock ’18: ACM Symposium on Neural Gaze Detection; June 03–05, 2018; Woodstock, NYbooktitle: Woodstock ’18: ACM Symposium on Neural Gaze Detection, June 03–05, 2018, Woodstock, NYprice: 15.00isbn: 978-1-4503-XXXX-X/18/06

1. Introduction

ACM’s consolidated article template, introduced in 2017, provides a consistent  style for use across ACM publications, and incorporates accessibility and metadata-extraction functionality necessary for future Digital Library endeavors. Numerous ACM and SIG-specific  templates have been examined, and their unique features incorporated into this single new template.

If you are new to publishing with ACM, this document is a valuable guide to the process of preparing your work for publication. If you have published with ACM before, this document provides insight and instruction into more recent changes to the article template.

The “acmart” document class can be used to prepare articles for any ACM publication — conference or journal, and for any stage of publication, from review to final “camera-ready” copy, to the author’s own version, with very few changes to the source.

2. Background

As noted in the introduction, the “acmart” document class can be used to prepare many different kinds of documentation — a double-blind initial submission of a full-length technical paper, a two-page SIGGRAPH Emerging Technologies abstract, a “camera-ready” journal article, a SIGCHI Extended Abstract, and more — all by selecting the appropriate template style and template parameters.

This document will explain the major features of the document class. For further information, the  User’s Guide is available from https://www.acm.org/publications/proceedings-template.

2.1. Use Case

The primary parameter given to the “acmart” document class is the template style which corresponds to the kind of publication or SIG publishing the work. This parameter is enclosed in square brackets and is a part of the documentclass command:

  \documentclass[STYLE]{acmart}

Journals use one of three template styles. All but three ACM journals use the acmsmall template style:

  • acmsmall: The default journal template style.

  • acmlarge: Used by JOCCH and TAP.

  • acmtog: Used by TOG.

The majority of conference proceedings documentation will use the acmconf template style.

  • acmconf: The default proceedings template style.

  • sigchi: Used for SIGCHI conference articles.

  • sigchi-a: Used for SIGCHI “Extended Abstract” articles.

  • sigplan: Used for SIGPLAN conference articles.

2.2. Datasets

In addition to specifying the template style to be used in formatting your work, there are a number of template parameters which modify some part of the applied template style. A complete list of these parameters can be found in the  User’s Guide.

Frequently-used parameters, or combinations of parameters, include:

  • anonymous,review: Suitable for a “double-blind” conference submission. Anonymizes the work and includes line numbers. Use with the \acmSubmissionID command to print the submission’s unique ID on each page of the work.

  • authorversion: Produces a version of the work suitable for posting by the author.

  • screen: Produces colored hyperlinks.

This document uses the following string as the first command in the source file:

\documentclass[sigconf,authordraft]{acmart}

3. Methods

Modifying the template — including but not limited to: adjusting margins, typeface sizes, line spacing, paragraph and list definitions, and the use of the \vspace command to manually adjust the vertical spacing between elements of your work — is not allowed.

Your document will be returned to you for revision if modifications are discovered.

3.1. Risk Prediction Model

3.2. Post-hoc Explainers

3.3. Guideline Contextualization

4. Results and Evaluation

The “acmart” document class requires the use of the “Libertine” typeface family. Your  installation should include this set of packages. Please do not substitute other typefaces. The “lmodern” and “ltimes” packages should not be used, as they will override the built-in typeface families.

4.1. Initial Results

4.2. Expert Feedback

5. Conclusion

The title of your work should use capital letters appropriately - https://capitalizemytitle.com/ has useful rules for capitalization. Use the title command to define the title of your work. If your work has a subtitle, define it with the subtitle command. Do not insert line breaks in your title.

If your title is lengthy, you must define a short version to be used in the page headers, to prevent overlapping text. The title command has a “short title” parameter:

  \title[short title]{full title}

6. Acknowledgments

This work is supported by IBM Research AI through the AI Horizons Network.

7. Appendices

If your work needs an appendix, add it before the “\end{document}” command at the conclusion of your source document.

Start the appendix with the “appendix” command:

  \appendix

and note that in the appendix, sections are lettered, not numbered. This document has two appendices, demonstrating the section and subsection identification method.

8. SIGCHI Extended Abstracts

The “sigchi-a” template style (available only in  and not in Word) produces a landscape-orientation formatted article, with a wide left margin. Three environments are available for use with the “sigchi-a” template style, and produce formatted output in the margin:

  • sidebar: Place formatted text in the margin.

  • marginfigure: Place a figure in the margin.

  • margintable: Place a table in the margin.

Acknowledgements.
This work is supported by IBM Research AI through the AI Horizons Network.